| 名稱 | Recombinant Human FGF-basic （154 a.a.） |
| 型號 | |
| 更新時間 | 2023-09-24 |
| 特點 | FGF-basic是23已知FGF家族的成員之一。這個家庭中發揮核心作用的蛋白質在產前發展和產后的生長和再生各種組織,通過促進細胞增殖和分化。FGF-basic non-glycosylated肝素結合生長因子,表示在大腦中,垂體,腎、視網膜、骨頭、睪丸、腎上腺肝、單核細胞、上皮細胞和內皮細胞。重組人類FGF-basic 17.2 kDa蛋白由154個氨基酸殘基組成。使用所有無動物生產試劑。} |
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- 詳細內容
一.產品名稱：Recombinant Human FGF-basic
二.貨號Catalog Number:AF-100-18B
三.同義Synonyms:Fibroblast Growth Factor-basic, FGF-2, HBGF-2, Prostatropin
四.描述Description:
FGF-basic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-basic is a non-glycosylated heparin binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland liver, monocytes, epithelial cells and endothelial cells. FGF-basic signals through FGFR 1b, 1c, 2c, 3c and 4. Recombinant human FGF-basic is a 17.2 kDa protein consisting of 154 amino acid residues. Manufactured using all non-animal reagents.
五.AA序列AA Sequence:
AAGSITTLPA LPEDGGSGAF PPGHFKDPKR LYCKNGGFFL RIHPDGRVDG VREKSDPHIK LQLQAEERGV VSIKGVCANR YLAMKEDGRL LASKCVTDEC FFFERLESNN YNTYRSRKYT SWYVALKRTG QYKLGSKTGP GQKAILFLPM SAKS
六.來源Source:E.coli
七.純度Purity:Greater than 95% by SDS-PAGE gel and HPLC analyses.
八.生物活性Biological Activity:
Assay #1: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors is ≤ 0.5ng/ml corresponding to a specific activity of ≥ 2 x 106 units/mg.
Assay #2: The ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.
九.交叉性Cross Reactivity:
Cow, Dog, Frog, Hamster, Monkey, Mouse, Pig, Rabbit, Rat, Sheep, Human + Mouse, Rat + Chicken, Human, Chicken, Horse, N/A, Human + Virus
十.產地：美國Peprotech
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電話/傳真：13366128764
手機：15311648455
地址：北京市海淀區廂黃旗2號樓1層4-179室