| 名稱 | Recombinant Human TPO |
| 型號 | |
| 更新時間 | 2023-09-24 |
| 特點 | TPO is a lineage specific growth factor, produced in the liver, kidney and skeletal muscle. It stimulates the proliferation and maturation of megakaryocytes。} |
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- 詳細內容
一.產品名稱：Recombinant Human TPO
二.產地：美國Peprotech
三.Catalog Number:AF-300-18
四.Synonyms:Thrombopoietin, Megakaryocyte colony-stimulating factor, c-MPL Ligand, MGDF
五.Description:
TPO is a lineage specific growth factor, produced in the liver, kidney and skeletal muscle. It stimulates the proliferation and maturation of megakaryocytes, and promotes increased circulating levels of plaets in vivo. TPO signals through the c-mpl receptor and acts as an important regulator of circulating plaets. Human and murine TPO exhibits cross-species reactivity. Recombinant human TPO is a fully biologically active 174 amino acid polypeptide (18.6 kDa), which contains the erythropoietin-like domain of the full length TPO protein. Manufactured using all non-animal reagents.
六.AA Sequence:
SPAPPACDLR VLSKLLRDSH VLHSRLSQCP EVHPLPTPVL LPAVDFSLGE WKTQMEETKA QDILGAVTLL LEGVMAARGQ LGPTCLSSLL GQLSGQVRLL LGALQSLLGT QLPPQGRTTA HKDPNAIFLS FQHLLRGKVR FLMLVGGSTL CVRRAPPTTA VPSRTSLVLT LNEL
七.Source:E.coli
八.Purity:Greater than 98% by SDS-PAGE gel and HPLC analyses.
九.Biological Activity:
The ED50 as determined by the dose-dependent stimulation of the proliferation of human MO7e cells was found to be ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 106 units/mg.
十.Cross Reactivity:Monkey, Mouse, Human, Rat, Human + Mouse
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電話/傳真：13366128764
手機：15311648455
地址：北京市海淀區廂黃旗2號樓1層4-179室